Treatment of Low-Blast Count AML using Hypomethylating Agents
نویسندگان
چکیده
منابع مشابه
Treatment of Low-Blast Count AML using Hypomethylating Agents
In 2002, the WHO classification reduced the proportion of blasts in the bone marrow (BM) necessary for the diagnosis of acute myeloid leukemia (AML) from 30% to 20%, eliminating the RAEB-t subtype of myelodysplastic syndromes (MDS). However, this AML subtype, defined as low-blast count AML (LBC-AML, with 20-30% BM-blasts) is characterized by peculiar features, as increased frequency in elderly ...
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which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Successful re-treatment with azacitidine in a patient with low blast count AML transformed from MDS after suspension of this agent TO THE EDITOR: The treatment approach to acute myeloid leukemia (AML) transformed from high-risk myelodys-plastic syndrome (MDS...
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We report five patients who had greater than 30% peripheral blasts and less than 30% marrow blasts. By the current standards these cases would be classified as myelodysplastic syndrome. Four of five patients progressed to acute leukemia within approximately 1 1/2 months of developing greater than 30% peripheral blasts. Two of these four patients had evidence of acute leukemia by criteria other ...
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ژورنال
عنوان ژورنال: Mediterranean Journal of Hematology and Infectious Diseases
سال: 2017
ISSN: 2035-3006
DOI: 10.4084/mjhid.2017.045